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Abstrak :
Latar Belakang : Salah satu efek samping yang dapat muncul dari pengobatan pada klien TB diantaranya adalah Efek kehilangan nafsu makan, mual, demam, nyeri sendi dan warna kemerahan pada kulit serta warna kemerahan pada air seni, Penelitian yang dilakukan sebelumnya menyatakan bahwa efek samping yang dirasakan oleh klien menjadi factor yang menyebabkan ketidakpatuhan klien dengan kehilangan efikasi diri klien yang terdiagnosa tuberculosis. Tujuan : Tujuan penelitian ini adalah untuk melihat efek dari konseling terhadap kepatuhan dalam minum obat pada pasien dengan TB Paru. Metode : Desain penelitian yang digunakan pada penelitian ini adalah quasy experiment dengan dua kelompok perlakuan, jumlah sampel pada penelitian ini adalah sebanyak 32 responden dengan 16 responden perkelompok. Intervensi yang diberikan pada penelitian ini adalah pemberian konseling selama 4 sesi kepada kelompok intervensi dan edukasi pada kelompok kontrol. Analisa statistic yang digunakan pada penelitian ini adalah uji karakteristik univariat, bivariat dengan uji paired t-test dan independent t-test. Hasil : Hasil penelitian yang dilakukan didapatkan pengaruh yang signifikan terhadap kepatuhan pada kelompok intervensi dengan p-value 0,001, dan efikasi diri dengan nilai p-value 0,001. Sedangkan pada kelompok kontrol hanya signifikan pada efikasi diri dengan p-value 0,009 tetapi tidak signifikan pada tingkat kepatuhan dengan p-value 0,078. Simpulan: Kesimpulan pada penelitian ini yaitu konseling sangat efektif terhadap peningkatan efikasi dalam kepatuhan minum obat pada pasien TB paru. Intervensi ini menjadi tindakam yang sangat direkomendasikan terutama untuk meningkatkan efikasi dan kepatuhan pada pasien TB ......Background: One of the side effects that can arise from treatment on TB clients include the effects of loss of appetite, nausea, fever, joint pain and redness of the skin and redness of the urine. Previous research stated that the side effects felt by clients were a factor causing client non-compliance with the loss of self-efficacy of clients diagnosed with tuberculosis. Purpose: The purpose of this study was to see the effect of counseling on adherence to taking medication in patients with pulmonary TB. Method: The research design used in this study was a quasy experiment with two treatment groups, the number of samples in this study were 32 respondents with 16 respondents per group. The interventions provided in this study were counseling for 4 sessions to the intervention group and education to the control group. Statistical analysis used in this study were univariate, bivariate characteristic tests with paired t tests and independent t tests. Results: The results of the research conducted showed that there was a significant effect on compliance in the intervention group with a p-value of 0.001, and self-efficacy with a p-value of 0.001. Whereas in the control group it was only significant in self-efficacy with a p-value of 0.009 but not significant in the level of compliance with a p-value of 0.078. Conclusion: The conclusion in this study is that counseling is very effective in increasing the efficacy of medication adherence in pulmonary TB patients. This intervention is highly recommended especially to increase efficacy and compliance in TB patients.

Abstrak :
Epilepsi merupakan penyakit neurologis yang menyerang segala usia. Diperlukan pengobatan jangka panjang untuk mencegah kekambuhan. Kepatuhan adalah hal yang penting dalam pengobatan epilepsi. Tujuan penelitian ini adalah untuk mengetahui gambaran kepatuhan minum obat pada pasien epilepsi dan faktor-faktor yang mempengaruhinya. Metode yang digunakan adalah deskriptif analitik dengan desain crossectional. Jumlah sampel dalam penelitian ini sebanyak 102. Alat ukur yang digunakan adalah kuesioner kepatuhan, kuesioner pengetahuan, kuesioner dukungan keluarga, kuesioner ketersediaan sarana dan fasilitas kesehatan, kuesioner, keyakinan, dan kuesioner motivasi. Hasil penelitian menunjukkan bahwa tingkat kepatuhan minum obat masih rendah (49%). Analisis dengan chi square didapatkan ada hubungan antara jenis kelamin (p=0,003), ketersediaan sarana dan fasilitas kesehatan (p=0.036), dan keyakinan (p=0,038) dengan kepatuhan minum obat. Rekomendasi dari penelitian ini adalah perlunya meningkatkan edukasi dan pemberian informasi mengenai penyakit dan pengobatan terhadap pasien epilepsi. ......Epilepsy is a neurological disease that affects all ages. Long-term treatment is needed to prevent recurrence. Adherence is important in the treatment of epilepsy. The purpose of this study was to determine the description of medication adherence in epilepsy patients and the factors that influence it. The method used is descriptive analytic with a cross-sectional design. The number of samples in this study was 102. The measuring instruments used were compliance questionnaires, knowledge questionnaires, family support questionnaires, questionnaires on the availability of health facilities and facilities, questionnaires, beliefs, and motivation questionnaires. The results showed that the level of adherence to taking medication was still low (49%). Chi-square analysis showed that there was a relationship between gender (p=0.003), availability of health facilities and facilities (p=0.036), and confidence (p=0.038) with medication adherence. The recommendation from this study is the need to increase education and provide information about the disease and treatment of epilepsy patients.

Abstrak :
Kepatuhan pasien Lupus Eritematosus Sistemik (LES) berperan penting dalam mencapai aktivitas penyakit yang terkontrol. Penelitian ini bertujuan untuk mengetahui prevalensi ketidakpatuhan, faktor-faktor yang berhubungan dengan ketidakpatuhan, dan hambatan minum obat pada pasien LES. Data potong lintang diperoleh dari pasien Poliklinik Alergi-Imunologi RSUPN Dr. Cipto Mangunkusumo secara konsekutif pada Juli–Agustus 2023. Dilakukan evaluasi terhadap ketidakpatuhan pengobatan (self-report medication-taking behaviour measure for thai patients scale; MTB-Thai), komorbiditas, jumlah obat, aktivitas penyakit (skor MEX-SLEDAI), depresi (Hospital Anxiety and Depression Scale; HADS), dan hambatan lain dalam pengobatan (Identification of Medication Adherence Barriers Questionnaire; IMAB-Q 30). Data kategorik dianalisis dengan uji Chi-square atau Fisher, sedangkan data numerik dianalisis dengan uji Mann-Whitney. Dari 100 pasien LES dewasa, mayoritas merupakan perempuan (97%), dewasa muda (61%), menamatkan pendidikan tinggi (48%), dan memiliki aktivitas penyakit remisi˗ringan (90%). Median (IQR) jumlah obat yang dikonsumsi 6 (5–8). Prevalensi ketidakpatuhan minum obat mencapai 27%. Tingkat pendidikan pasien ditemukan berhubungan dengan ketidakpatuhan (pendidikan menengah vs. pendidikan tinggi, 59,3% vs. 40,7%; p=0,035). Pasien yang tidak patuh memiliki skor hambatan minum obat yang lebih tinggi secara signifikan (p<0,001). Hambatan yang paling banyak dialami pasien yang tidak patuh adalah kekhawatiran terhadap efek samping dan mudah terdistraksi dari mengonsumsi obat-obatan. ......Medication adherence among patients with systemic lupus erythematosus (SLE) is essential to achieve controlled disease activity. This study aimed to investigate the prevalence of non-adherence, associated factors, and medication adherence barriers among patients with SLE. Cross-sectional data were obtained from consecutive patients at Allergy-Immunology Clinic Cipto Mangunkusumo Hospital between July–August 2023. Evaluation was conducted on medication non-adherence (self-report medication-taking behavior measure for thai patients scale), comorbidities, number of medications, disease activity (MEX-SLEDAI score), depression (Hospital Anxiety and Depression Scale), and other adherence barriers (Identification of Medication Adherence Barriers Questionnaire-30). Categorical data were analyzed with Chi-square or Fisher test, while numerical data were analyzed with Mann-Whitney test. Of 100 adult SLE patients, most were female (97%), young adult (61%), completed higher education (48%), and had remission˗mild disease activity (90%). The median (IQR) number of medications consumed was 6 (5–8). The prevalence of medication non-adherence was 27%. Patient's educational level was found to be associated with non-adherence (secondary education vs. higher education, 59.3% vs. 40.7%; p=0.035). Non-adherent patients had significantly higher medication adherence barrier scores (p<0.001). The most common barriers experienced by non-adherent patients were concerns about harmful side effects and easily distracted from taking medications.

Abstrak :
Tuberkulosis merupakan salah satu penyakit menular yang disebabkan oleh bakteri Mycobacterium tuberculosis, bakteri ini dapat menyebabkan infeksi laten dan infeksi yang aktif progresif. Pengobatan TB aktif minimal dua kombinasi obat biasanya tiga atau empat obat dengan durasi pengobatan minimal 6 bulan Pengobatan yang harus dijalani pasien yaitu dua bulan pertama fase intensif dengan empat kombinasi OAT dan dilanjutkan dua bulan fase lanjutan dengan kombinasi dua OAT. Regimen yang diberikan berupa kombinasi lini pertama etambutol, isoniazid, pirazinamid, dan rifampisin. Pengobatan Tuberculosis yang lama dan efek samping menjadi salah satu rendahnya kepatuhan pasien Tuberculosis dalam mengkonsumsi OAT. Lamanya durasi pengobatan kadang membuat pasien menjadi jenuh dan putus asa. Pengawas Menelan Obat atau yang dikenal dengan PMO yang bertugas mendampingi, memberi edukasi, dan memantau pasien Tuberkulosis. Apotek berperan dalam penunjang pelayanan kesehatan promotive, preventif, kuratif, rehabilitatif, dan tradisional. Penyampaian edukasi dan pemantauan yang dilakukan oleh suatu apotek merupakan bagian dari penunjang pelayanan promotive, preventif dan rehabilitative. Penggunaan tekonologi Whatsapp memudahkan untu penyampaian informasi kepada pasien dan masyarakat. Tujuan dari pelaksanaan tugas khusus ini adalah meningkatkan kepatuhan dan mengedukasi pentingnya menelan obat tuberkulosis dengan baik dan benar kepada pasien Tuberkulosis yang menjadi pelanggan Apotek Roxy Pondok Labu melalui broadcast WhatsApp menggunakan sarana infografis untuk memudahkan pasien memahami pentingnya kepatuhan menelan obat. Kegiatan edukasi untuk kepatuhan menelan obat dapat diwujudkan dengan memberikan informasi mengenai kepatuhan menelan obat dan beberapa cara sebagai pengingat menelan obat melalui pesan broadcast Whatsapp dan poster hal ini tidak hanya berguna untuk pasien tetapi juga bagi orang orang terdekat pasien. ......Tuberculosis is an infectious disease caused by the bacterium Mycobacterium tuberculosis, which can cause latent infection and active progressive infection. Treatment of active TB is a minimum of two drug combinations usually three or four drugs with a minimum treatment duration of 6 months. The treatment that patients must undergo is the first two months of the intensive phase with four OAT combinations and continued for two months of the continuation phase with a combination of two OAT. The regimen is a first-line combination of ethambutol, isoniazid, pyrazinamide and rifampicin. The long duration of Tuberculosis treatment and side effects are one of the reasons for the low compliance of Tuberculosis patients in taking OAT. The long duration of treatment sometimes makes patients bored and desperate. Drug Swallowing Supervisor or known as PMO is in charge of accompanying, educating, and monitoring Tuberculosis patients. Pharmacies play a role in supporting promotive, preventive, curative, rehabilitative, and traditional health services. The delivery of education and monitoring carried out by a pharmacy is part of supporting promotive, preventive and rehabilitative services. The use of WhatsApp technology makes it easier to convey information to patients and the public. The purpose of this special assignment is to increase compliance and educate the importance of swallowing tuberculosis drugs properly and correctly to Tuberculosis patients who are customers of Roxy Pondok Labu Pharmacy through WhatsApp broadcasts using infographic facilities to make it easier for patients to understand the importance of drug swallowing compliance. Educational activities for drug swallowing compliance can be realized by providing information about drug swallowing compliance and several ways as a reminder to swallow drugs through WhatsApp broadcast messages and posters, this is not only useful for patients but also for people closest to patients.

Abstrak :
[ABSTRAK
Latar belakang dan tujuan: Akne vulgaris (AV) adalah penyakit peradangan menahun unit pilosebasea yang bersifat swasirna, ditandai dengan lesi pleomorfik berupa papul, komedo, pustul, dan nodul. Pengobatan AV memerlukan waktu yang cukup lama. Penyakit menahun dengan waktu pengobatan yang lama, berdampak terhadap kepatuhan pasien. Kepatuhan pengobatan topikal lebih rendah daripada sistemik. Hanya akne vulgaris ringan (AVR) yang diterapi menggunakan obat-obatan topikal saja. Layanan pesan singkat merupakan salah satu cara yang praktis dan efisien dalam upaya meningkatkan kepatuhan pengobatan AV, dengan pertimbangan prevalensi AV lebih banyak pada usia remaja dan dewasa muda yang merupakan pengguna terbanyak layanan tersebut. Dengan layanan ini, diharapkan pasien tidak lupa menggunakan obat topikal pada AVR. Penelitian ini dilakukan untuk mengetahui efektivitas penggunaan pesan singkat elektronik terhadap kepatuhan pengobatan AVR.

Metode: Studi eksperimen dengan desain randomized controlled trial (RCT) terhadap pasien AVR usia 15-25 tahun yang berobat ke Poliklinik Ilmu Kesehatan Kulit dan Kelamin (IKKK) Rumah Sakit dr. Cipto Mangunkusumo (RSCM). Penelitian ini melibatkan 2 kelompok, yaitu: kelompok intervensi yang mendapat pesan singkat elektronik dan kelompok kontrol. Kedua kelompok diberi pengobatan tretinoin krim 0,05% dan/atau klindamisin gel 1,2% selama 6 minggu.

Hasil: Tidak terdapat perbedaan bermakna antara kepatuhan pengobatan AVR kelompok kontrol dengan kelompok intervensi pada minggu kedua (p=0,376) dan keempat (p=0,432). Namun pada minggu keenam, kelompok intervensi secara bermakna lebih patuh daripada kelompok kontrol (p=0,032).

Kesimpulan: Pesan singkat elektronik meningkatkan kepatuhan pengobatan AVR terutama pada minggu keenam di Poliklinik IKKK RSCM.

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ABSTRACT
Background and objectives: Acne vulgaris (AV) is a self limited, chronic inflammatory disease of pilosebaceous unit, characterized by pleomorphic lesions consist of papules, comedones, pustules, and nodules. Acne vulgaris requires a long duration of treatment. Chronic disease with a long duration of therapy usually has an impact on adherence. Topical therapy adherence is lower than systemic. Only mild AV is treated with topical medications. Electronic text messaging is a practical and efficient method in order to improve adherence to AV therapy, with a consideration of the AV prevalence are more on teens and young adults who are the majority users of electronic text messaging service. With this method, patients are expected not to forget the use of medication. This study was conducted to determine the effectiveness of electronic text messaging to improve adherence of mild AV therapy.

Methods: Experimental study, randomized controlled trial (RCT) to mild AV patients, age 15-25 years old who came to Dermatology and Venereology Clinic dr. Cipto Mangunkusumo Hospital. This study involved two groups: intervention group who received electronic text messaging, and the contrary is the control group. Both groups were prescribed tretinoin 0,05% cream and/or clindamycin 1,2% gel for six weeks.

Results: There were no significant differences in adherence of mild AV therapy between both groups in the second (p = 0.376) and fourth week (p = 0.432). The intervention group was significantly higher in terms of adherence than the control group in the sixth week (p = 0.032).

Conclusions: Electronic text messaging improve adherence of mild AV therapy especially in the sixth week at Dermatology and Venereology Clinic dr. Cipto Mangunkusumo Hospital.;Background and objectives: Acne vulgaris (AV) is a self limited, chronic inflammatory disease of pilosebaceous unit, characterized by pleomorphic lesions consist of papules, comedones, pustules, and nodules. Acne vulgaris requires a long duration of treatment. Chronic disease with a long duration of therapy usually has an impact on adherence. Topical therapy adherence is lower than systemic. Only mild AV is treated with topical medications. Electronic text messaging is a practical and efficient method in order to improve adherence to AV therapy, with a consideration of the AV prevalence are more on teens and young adults who are the majority users of electronic text messaging service. With this method, patients are expected not to forget the use of medication. This study was conducted to determine the effectiveness of electronic text messaging to improve adherence of mild AV therapy. Methods: Experimental study, randomized controlled trial (RCT) to mild AV patients, age 15-25 years old who came to Dermatology and Venereology Clinic dr. Cipto Mangunkusumo Hospital. This study involved two groups: intervention group who received electronic text messaging, and the contrary is the control group. Both groups were prescribed tretinoin 0,05% cream and/or clindamycin 1,2% gel for six weeks. Results: There were no significant differences in adherence of mild AV therapy between both groups in the second (p = 0.376) and fourth week (p = 0.432). The intervention group was significantly higher in terms of adherence than the control group in the sixth week (p = 0.032). Conclusions: Electronic text messaging improve adherence of mild AV therapy especially in the sixth week at Dermatology and Venereology Clinic dr. Cipto Mangunkusumo Hospital.;Background and objectives: Acne vulgaris (AV) is a self limited, chronic inflammatory disease of pilosebaceous unit, characterized by pleomorphic lesions consist of papules, comedones, pustules, and nodules. Acne vulgaris requires a long duration of treatment. Chronic disease with a long duration of therapy usually has an impact on adherence. Topical therapy adherence is lower than systemic. Only mild AV is treated with topical medications. Electronic text messaging is a practical and efficient method in order to improve adherence to AV therapy, with a consideration of the AV prevalence are more on teens and young adults who are the majority users of electronic text messaging service. With this method, patients are expected not to forget the use of medication. This study was conducted to determine the effectiveness of electronic text messaging to improve adherence of mild AV therapy. Methods: Experimental study, randomized controlled trial (RCT) to mild AV patients, age 15-25 years old who came to Dermatology and Venereology Clinic dr. Cipto Mangunkusumo Hospital. This study involved two groups: intervention group who received electronic text messaging, and the contrary is the control group. Both groups were prescribed tretinoin 0,05% cream and/or clindamycin 1,2% gel for six weeks. Results: There were no significant differences in adherence of mild AV therapy between both groups in the second (p = 0.376) and fourth week (p = 0.432). The intervention group was significantly higher in terms of adherence than the control group in the sixth week (p = 0.032). Conclusions: Electronic text messaging improve adherence of mild AV therapy especially in the sixth week at Dermatology and Venereology Clinic dr. Cipto Mangunkusumo Hospital., Background and objectives: Acne vulgaris (AV) is a self limited, chronic inflammatory disease of pilosebaceous unit, characterized by pleomorphic lesions consist of papules, comedones, pustules, and nodules. Acne vulgaris requires a long duration of treatment. Chronic disease with a long duration of therapy usually has an impact on adherence. Topical therapy adherence is lower than systemic. Only mild AV is treated with topical medications. Electronic text messaging is a practical and efficient method in order to improve adherence to AV therapy, with a consideration of the AV prevalence are more on teens and young adults who are the majority users of electronic text messaging service. With this method, patients are expected not to forget the use of medication. This study was conducted to determine the effectiveness of electronic text messaging to improve adherence of mild AV therapy. Methods: Experimental study, randomized controlled trial (RCT) to mild AV patients, age 15-25 years old who came to Dermatology and Venereology Clinic dr. Cipto Mangunkusumo Hospital. This study involved two groups: intervention group who received electronic text messaging, and the contrary is the control group. Both groups were prescribed tretinoin 0,05% cream and/or clindamycin 1,2% gel for six weeks. Results: There were no significant differences in adherence of mild AV therapy between both groups in the second (p = 0.376) and fourth week (p = 0.432). The intervention group was significantly higher in terms of adherence than the control group in the sixth week (p = 0.032). Conclusions: Electronic text messaging improve adherence of mild AV therapy especially in the sixth week at Dermatology and Venereology Clinic dr. Cipto Mangunkusumo Hospital.]

Abstrak :
ABSTRAK
Kanker Payudara KPD merupakan jenis penyakit Kanker dengan risiko insidensi mortalitas tertinggi di Indonesia. Tesis ini membahas tingkat kepatuhan dan faktor ndash; faktor yang mempengaruhi kepatuhan pengobatan pasien Kanker Payudara KPD yang menjalani terapi hormonal dengan Tamoxifen pada pasien RS Kanker Dharmais tahun 2018. Penelitian ini adalah penelitian observasional dengan desain potong lintang cross-sectional . Penelitian diikuti oleh sebanyak 109 orang responden. Tingkat kepatuhan pengobatan dinilai melalui kuesioner MARS-5 yang dimodifikasi. Karaktersitik sosiodemografi dan klinis diperoleh dari wawancara dengan menggunakan kuesioner. Hasil penelitian menunjukkan tingkat kepatuhan pengobatan KPD dengan Tamoxifen adalah 90,9 dengan proporsi pasien yang patuh adalah 75,2 82 dari 109 orang . Umur pasien, pendapatan, tingkat pendidikan, pemberian informasi dan edukasi tentang pengobatan, dan tingkat pengetahuan pasien mempunyai pengaruh yang bermakna dalam mempengaruhi tingkat kepatuhan pengobatan. Analisis multivariat menunjukkan bahwa Umur responden, tingkat pendidikan, tingkat pengetahuan merupakan faktor yang paling berpengaruh dan menentukan tingkat kepatuhan pengobatan. Tingkat Pendidikan merupakan variabel yang paling besar pengaruhnya terhadap kepatuhan pengobatan. Melalui penelitian ini disarankan untuk memberikan perhatian khusus untuk pasien ndash; pasien dengan karakteristik tertentu seperti pasien dengan tingkat pendidikan atau berpendapatan rendah.

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ABSTRACT
Breast Cancer BC is a type of cancer disease with the highest incidence of mortality in Indonesia. The focus of the study was to determine the level of adherence and factors influencing the adherence of the treatment of BC patients undergoing hormonal therapy with Tamoxifen in patients with Dharmais Cancer Hospital in year 2018. The study is an observational study with a cross sectional design. The study was followed by 109 respondents. Medication adherence levels assessed via questionnaire MARS 5 modified. Sociodemographic and clinical characteristic obtained from interviews using questionnaires. The results showed that the medication adherence level of KPD with Tamoxifen was 90.9 with the proportion of adherent patients was 75.2 82 of 109 patients . Patient age, income, education level, information and education about treatment, patient 39 s level of knowledge have a significant influence on the level of medication adherence. Multivariate analysis showed that the age of respondents, level of education, level of knowledge is the most influential factor and determine the level of treatment adherence. Education level is the variable that has the greatest effect on medication adherence. Through this study, it is advisable to pay particular attention to patients with certain characteristics such as patients with low education or low income levels.

Abstrak :
Pendahuluan – Kasus HIV di Indonesia dilaporkan terus meningkat setiap tahunnya, secara kumulatif kasus HIV yang dilaporkan hingga Maret 2022 sebanyak 329.581 orang atau 60% dari estimasi jumlah orang yang hidup dengan HIV/AIDS (ODHA) sebanyak 543.100 orang, sedangkan kasus AIDS sebanyak 137.397 orang atau 25%. Berdasarkan data dan pelaporan dari tahun 2022 dan Sekitar 214.819 orang memenuhi syarat untuk pengobatan ARV. Dari jumlah tersebut, hanya 180.843 orang yang mendapatkan obat ARV dan 39.543 menjalani post-absence care (LFU). Di antara pasien HIV yang menerima ARV, 21,87% adalah pasien yang tidak patuh. Tujuan penelitian ini adalah memanfaatkan peer group support untuk mengurangi stigma negatif dan meningkatkan kepatuhan minum obat ARV di Lapas DKI Jakarta. Metodologi/Pendekatan – Rancangan penelitian ini adalah Quasy Experiment dengan pre test dan post test group. Pada penelitian ini, desain eksperimen yang digunakan adalah one group pretest posttest yang dilakukan sebelum diberikan treatment dan posttest yang dilakukan setelah diberikan treatment, sampel penelitian ini berjumlah 27 orang dengan teknik sampling purposif. Variabel bebas penelitian ini adalah intervensi peer support dan variabel terikat dalam penelitian ini adalah stigma dan kepatuhan minum obat ARV. Data dalam penelitian ini dianalisis dengan menggunakan statistik uji t berpasangan. Hasil: Hasil penelitian dengan uji t berpasangan menunjukkan hasil analisis bivariat sebelum dan sesudah intervensi peer support selisi rerata stigma 4,2 dengan SD 1,9 sedangkan tingkat kepatuhan selisi rerata sebelum dan setelah intervensi 4,8 dengan SD 1,3 setelah di uji statistic stigma dan kepatuhan didapat hasil uji paired tet p value 0,000<0,05 maka terdapat hubungan bermakna antara stigma dan kepatuhan sebelum dan setelah intervensi. Hasil penelitian dengan uji t berpasangan menunjukkan hasil analisis bivariat sebelum dan sesudah intervensi peer support selisi rerata stigma 4,2 dengan SD 1,9 sedangkan tingkat kepatuhan selisi rerata sebelum dan setelah intervensi 4,8 dengan SD 1,3 setelah di uji statistic stigma dan kepatuhan didapat hasil uji paired tet p value 0,000<0,05 maka terdapat hubungan bermakna antara stigma dan kepatuhan sebelum dan setelah intervensi. Implikasi: Hasil penelitian menunjukkan peran peer group terhadap stigma dan kepatuhan pada ODHA dapat membuktikan menurunkan stigma negatif terhadap ODHA dan meningkatkanya kepatuhan minum obat ARV. Diharapkan hasil penelitian ini menjadi referensi bagi pelayanan keperawatan dalam upaya meningkatnya kepatuhan sehingga mengurangi angka dari HIV menjadi AIDS, mengurangi infeksi oportunistik, meningkatkan jumlah CD 4 dan meningkatkanya qualitas hidup. ......Introduction – HIV cases in Indonesia are reported to continue to increase every year, cumulatively HIV cases reported up to March 2022 are 329,581 people or 60% of the estimated number of people living with HIV/AIDS (PLWHA) of 543,100 people, while AIDS cases are as many as 137,397 people or 25%. Based on data and reporting from 2022 and Approximately 214,819 people are eligible for ARV treatment. Of these, only 180,843 people received ARV drugs and 39,543 underwent post-absence care (LFU). Among HIV patients receiving ARVs, 21.87% were non-adherent patients. Purpose – The purpose of this study was to utilize peer group support to reduce negative stigma and increase adherence to taking ARV medication in the DKI Jakarta Prison. Methodology/Approach – The design of this research is Quasy Experiment with pre test and post test group. In this study, the experimental design used was one group pre-test post-test which was carried out before being given treatment and post-test which was carried out after being given treatment, a sample of this the study amounted to 27 people with a purposive sampling technique. The independent variable of this research is Peer support interventions and the dependent variables in this study were stigma and adherence to taking ARV medication. The data in this study were analyzed using the paired t-test statistic. Findings – The results of the study using paired t tests showed that the results of bivariateanalysis before and after peer support interventions had a mean difference of 4.2 with an SD of 1.9 while the average difference in the level of adherence before and after the intervention was 4.8 with an SD of 1.3 after being tested for stigma and statistics. Compliance was obtained from the results of the paired tet test p value 0.000 <0.05, so there was a significant relationship between stigma and adherence before and after the intervention. The results of the study using paired t tests showed that the results of bivariate analysis before and after peer support interventions had a mean difference of 4.2 with an SD of 1.9 while the average difference in the level of adherence before and after the intervention was 4.8 with an SD of 1.3 after being tested for stigma and statistics. Compliance was obtained from the results of the paired tet test p value 0.000 <0.05, so there was a significant relationship between stigma and adherence before and after the intervention. Implication –The results of the study show that the role of peer groups in stigma and adherence to PLWHA can prove to reduce negative stigma against PLWHA and increase adherence to taking ARV medication. It is hoped that the results of this study will become a reference for nursing services in an effort to increase adherence thereby reducing the number of HIV to AIDS, reducing opportunistic infections, increasing the number of CD 4 and increasing the quality of life.

Abstrak :
HIV merupakan masalah kesehatan masyarakat utama secara global. HIV memerlukan pengobatan seumur hidup sehingga kepatuhan terhadap pengobatan antiretroviral sangat diperlukan oleh ODHIV agar mencapai keberhasilan pengobatan. Tesis ini mengkaji seberapa besar pengaruh tingkat kepatuhan terapi antiretroviral terhadap resiko kegagalan virologis yang dikur dari capaian supresi virus pada orang dengan HIV di Kota Bogor. Penelitian ini merupakan penelitian kuantitatif  dengan metode observasional analitik dan desain kasus kontrol  melalui pemanfaatan data SIHA versi 1.7 di  11 fasilitas kesehatan. Hasil penelitian didapatkan orang dengan HIV di Kota Bogor dengan kepatuhan terapi rendah  memiliki resiko 13,21 kali (95% CI: 6,00-29,06; p: 0,000) menyebabkan virus tidak supresi. Disarankan untuk optimalisasi konseling kepatuhan melalui peran konselor dalam menggali hambatan kepatuhan pada orang dengan HIV di layanan. ......HIV is a major public health problem globally. HIV requires lifelong treatment so that adherence to antiretroviral treatment is needed by PLHIV to achieve treatment success. This thesis examines how much influence the level of adherence to antiretroviral therapy has on the risk of virological failure as measured by the achievement of virus suppression in people living with HIV in Bogor City. This research is a quantitative study using analytic observational methods and a case-control design using SIHA version 1.7 data in 11 health facilities. The results of the study found that people with HIV in Bogor City with low adherence to therapy had a 13.21 times (95% CI: 6.00-29.06; p: 0.000) risk of causing the virus to not be suppressed. It is suggested to optimize adherence counseling through the counselor role in exploring adherence barriers in people with HIV in services.

Abstrak :
Kepatuhan merupakan salah satu permasalahan pada pasien hemodialisa yang mengalami penyakit ginjal kronis. Ketidakpatuhan dapat menyebabkan kegagalan terapi sehingga menurunkan kualitas hidup pasien, meningkatkan angka mortalitas dan morbiditas. Tujuan penelitian adalah mengetahui faktor-faktor yang berhubungan dengan kepatuhan pasien CKD dengan hemodialisa di RSPAU dr. Esnawan Antariksa Halim Perdanakusuma Jakarta. Desain penelitian adalah Cross Sectional dengan jumlah sampel 157 responden, yang didapat dengan consecutive sampling. Metode pengumpulan data dengan cara pengisian kuesioner. Analisis hasil penelitian menggunakan Chi-Square (bivariat) dengan α=0,05, didapatkan hubungan yang bermakna antara kepatuhan dengan usia (p=0,006), pendidikan (p=0,003), lamanya HD (p=0,015), motivasi (p=0,039) dan dukungan keluarga (p=0,014).

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Adherence is one of the problems in hemodialysis patients who have chronic kidney disease. Poor adherence could lead to treatment failure resulting in lower quality of life for patients, increase morbidity and mortality. The research objective was to determine the factors associated with CKD patient adherence with hemodialysis in RSPAU dr. Esnawan Antariksa Halim Perdanakusuma Jakarta. The study design is the Cross Sectional with 157 respondents, obtained by consecutive sampling. Methods of data collection by filling the questionnaire. Analysis of the results of research using the Chi-Square (bivariate) with α = 0.05, obtained a significant association between adherence with age (p = 0.006), education (p = 0.003), duration of HD (p = 0.015), motivation (p = 0.039) and family support (p = 0.014).

Abstrak :
ABSTRAK
Interdialytic Weight Gain (​IDWG) merupakan akumulasi cairan pada dua waktu dialisis yang dapat dipengaruhi ​oleh asupan cairan, natrium, dan tidak adekuatnya ultrafiltrasi. Kenaikan IDWG yang tinggi akan meningkatkan mortalitas. Penelitian ini bertujuan untuk mengetahui hubungan manajemen terapi dialisis kronis dengan IDWG. Desain penelitian ini adalah ​cross-sectional yang melibatkan 94 responden yang dipilih melalui consecutive sampling. Kepatuhan dinilai menggunakan kuesioner yang diadaptasi dari End Stage Renal Disease Adherence Quesstionaire. Hasil penelitian menunjukkan ada hubungan negatif yang sedang antara kepatuhan manajemen terapi dialisis kronis dengan IDWG (P value = 0,001), (r = - 0,49) artinya semakin tinggi kepatuhan manajemen terapi dialisis kronis maka IDWG akan semakin ringan. Pembatasan cairan dan makanan menunjukkan ada hubungan dengan IDWG (P value = 0,001), (r = -0,48); r = -0,38) untuk keduanya. Mayoritas pasien patuh terhadap manajemen terapi dialisis kronis (61,7%) dan IDWG terbanyak dalam kategori ringan (46,8%). Disarankan bagi perawat HD agar memilih strategi yang tepat dalam meningkatkan kepatuhan pasien HD untuk menurunkan IDWG.

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ABSTRACT
Interdialytic Weight Gain (IDWG) is an accumulation of fluid between two-time dialysis which influenced by fluid intake, sodium, and inadequate of ultrafiltration, the increase of IDWG may enhance mortality among haemodialysis patient. This study aims to identify the relationship between chronic dialysis therapy management and IDWG. The design of this study was cross-sectional, involved 94 respondents being selected by consecutive sampling. The adherence was assesed using questionnaire that was adapted from End Stage Renal Disease Adherence Qustionnaire. The result of the study shows there is a significant relationship between chronic dialysis therapy management and IDWG (P value = 0,001), (r = - 0,49) it means higher the adherence of chronic dialysis therapy management then IDWG will be lighter. Fluid restriction and diet restriction showed a relationship with IDWG (P value = 0,001), (r = -0,48; r = -0,38) respectively. Majority patients had adherence of chronic dialysis therapy management (61,7%) had IDWG in low category (46,8%). it can be suggested that nurses have to create appropriate strategies to increase patients' adherence in order to reduce IDWG on haemodialysis patients